Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15467164 | 0.91 | EPHX2 (0.40) | TRPV1ENPP2MGLLEPHX2P2RX7 | |
| SCHEMBL17857815 | 0.91 | TRPV1 (0.38) | TRPV1ENPP2MGLLEPHX2AOC3 | |
| SCHEMBL15468119 | 0.90 | TRPV1 (0.38) | TRPV1ENPP2MGLLEPHX2P2RX7 | |
| SCHEMBL15466506 | 0.90 | EPHX2 (0.42) | TRPV1ENPP2EPHX2P2RX7 | |
| SCHEMBL15467187 | 0.88 | EPHX2 (0.45) | EPHX2 | |
| SCHEMBL795219 | 0.83 | KDM4E (0.34) | ENPP2USP2CYP3A4 | |
| SCHEMBL12467240 | 0.82 | FAAH (0.40) | TRPV1ENPP2MGLLEPHX2AOC3 | |
| SCHEMBL794407 | 0.82 | EPHX2 (0.45) | TRPV1ENPP2EPHX2P2RX7 | |
| SCHEMBL792802 | 0.82 | EPHX2 (0.39) | TRPV1ENPP2MGLLEPHX2AOC3 | |
| SCHEMBL795686 | 0.81 | NR1H2 (0.34) | TRPV1EPHX2USP2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9375000-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-06-28 | — | — | US | disclosed |
| US-20140046069-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-02-13 | — | — | US | disclosed |
| EP-2616437-A1 | PESTICIDAL ARYLPYRROLIDINES | Bayer Intellectual Property GmbH (DE) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012035011-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2012-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140046069-A1 | PESTICIDAL ARYLPYRROLIDINES | DDT, ACHE, CAT | TRPV1 293/4885ENPP2 2913/4885MGLL 377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.