Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 2/20 | 0.57 |
| ▸ | HTR6 | P50406 | 9/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 7/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016279 | 0.79 | FADS1 (0.79) | FADS1HTR6GRM2HSD11B1ROCK2 | |
| SCHEMBL7805542 | 0.78 | HTR6 (0.65) | FADS1HTR6GRM2HSD11B1 | |
| SCHEMBL7775283 | 0.76 | FADS1 (0.65) | FADS1HTR6GRM2ADORA3AR | |
| SCHEMBL7807351 | 0.74 | FADS1 (0.55) | FADS1HTR6ARHSD11B1ROCK2 | |
| SCHEMBL6266797 | 0.74 | GRM2 (0.57) | FADS1GRM2 | |
| SCHEMBL12635405 | 0.72 | GRM2 (0.51) | FADS1GRM2 | |
| SCHEMBL4670666 | 0.71 | GRM2 (0.54) | FADS1GRM2 | |
| SCHEMBL4669702 | 0.71 | GRM2 (0.54) | FADS1GRM2 | |
| SCHEMBL2322579 | 0.71 | GRM2 (0.54) | FADS1GRM2 | |
| SCHEMBL7805594 | 0.71 | FADS1 (0.48) | FADS1HTR6GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255327-B1 | ANTIHYPOXC, ANTIISCHEMIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-07-03 | — | — | US | disclosed |