Hexane

Hexane

SCHEMBL7946812

CCCCCC.CCOC(=O)CCO.CCOC(=O)CCO.CCOC(=O)CCO.CCOC(=O)CCO.CCOC(=O)CCO.CCOC(=O)CCO.CCOC(=O)CCO.CCOC(=O)CCO.CCOC(=O)CCO.CCOC(=O)CCO.CCOC(=O)CCO.CCOC(=O)CCO.CCOC(=O)CCO.CCOC(=O)CCO.CCOC(=O)CCO.CCOC(=O)CCO.CCOC(=O)CCO.CCOC(=O)CCO.CCOC(=O)CCO.CCOC(=O)CCO.CCOC(=O)CCO.CCOC(=O)CCO.CCOC(=O)CCO.CCOC(=O)CCO.CCOC(=O)CCO.CCOC(=O)CCO.CCOC(=O)CCO.CCOC(=O)CCO.CCOC(=O)CCO.CCOC(=O)CCO

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.54
GAA P10253 1/20 0.54
SI P14410 1/20 0.54
MGAM2 Q2M2H8 1/20 0.54
DGKA P23743 1/20 0.54
CYP1A2 P05177 1/20 0.54
CYP4F2 P78329 1/20 0.48
CYP4A11 Q02928 1/20 0.48
PAM P19021 2/20 0.48
LMNA P02545 2/20 0.47
KDM4E B2RXH2 1/20 0.47
DUSP3 P51452 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
MGLL Q99685 1/20 0.46
TSHR P16473 1/20 0.46
MAPT P10636 1/20 0.46
ALDH1A1 P00352 2/20 0.44
PRKCA P17252 1/20 0.44
PRKCE Q02156 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexane SCHEMBL25882 1.00 MGAM (0.54) MGAMGAASIMGAM2DGKA
Hexane SCHEMBL8710112 0.98 MGAM (0.52) MGAMGAASIMGAM2DGKA
Heptane SCHEMBL200855 0.98 DGKA (0.57) MGAMGAASIMGAM2DGKA
Tetradecane SCHEMBL9947966 0.98 DGKA (0.57) MGAMGAASIMGAM2DGKA
Pentane SCHEMBL4415680 0.95 GAA (0.54) MGAMGAASIMGAM2DGKA
Hexane SCHEMBL16566680 0.94 DGKA (0.48) MGAMGAASIMGAM2DGKA
SCHEMBL936467 0.94 DGKA (0.64) DGKACYP1A2PAMLMNAKDM4E
Hexane SCHEMBL5329217 0.92 ALDH1A1 (0.54) MGAMGAASIMGAM2DGKA
Hexane SCHEMBL2346139 0.92 ALDH1A1 (0.54) MGAMGAASIMGAM2DGKA
SCHEMBL6403 0.91

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6271403-B1 PURE ANTIESTROGENS, OR ESTROGENIC ANTIESTROGENS WITH ESTROGENIC PARTIAL ACTION. SCHERING AKTIENGESELLSCHAFT (DE) 2001-08-07 US disclosed
US-5986115-A STEROIDS WITH FLUORO GROUPS AND ETHER OR ESTER GROUPS SCHERING AG (DE) 1999-11-16 US disclosed
US-5866560-A ESTROGEN INHIBITORS; TUMOR THERAPY; HORMONE REPLACEMENT THERAPY SCHERING AG (DE) 1999-02-02 US disclosed