Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MITF | O75030 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | PKM | P14618 | 5/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985731 | 0.94 | MAPT (0.55) | ALDH1A1MAPTL3MBTL1MITFMEN1 | |
| SCHEMBL4305038 | 0.91 | MAPT (0.51) | ALDH1A1MAPTL3MBTL1MITFMEN1 | |
| SCHEMBL3950152 | 0.88 | ALDH1A1 (0.53) | ALDH1A1MAPTL3MBTL1MITFMEN1 | |
| SCHEMBL4306692 | 0.88 | HDAC1 (0.42) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL7992052 | 0.86 | ALDH1A1 (0.55) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL3950155 | 0.86 | ALDH1A1 (0.46) | ALDH1A1MAPTL3MBTL1MITFMEN1 | |
| SCHEMBL3129608 | 0.85 | MAPT (0.58) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL3122360 | 0.84 | ALDH1A1 (0.59) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL7948285 | 0.84 | ALDH1A1 (0.58) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL4307521 | 0.83 | ALDH1A1 (0.49) | ALDH1A1MAPTL3MBTL1MITFMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010035032-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2010-04-01 | — | — | WO | disclosed |