Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.34 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7948067 | 0.98 | L3MBTL1 (0.36) | TSHRACHETDP1CYP2D6CYP2C19 | |
| SCHEMBL11571785 | 0.85 | TSHR (0.36) | TSHRACHETDP1CYP2D6CYP2C19 | |
| SCHEMBL11570019 | 0.82 | CYP2A13 (0.47) | TSHRTDP1CYP2C19ALDH1A1GAA | |
| SCHEMBL31355198 | 0.74 | KMT2A (0.32) | TSHRCYP2C19ALDH1A1ATM | |
| SCHEMBL11679024 | 0.70 | CYP3A4 (0.39) | TSHRTDP1CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL10914158 | 0.69 | TSHR (0.47) | TSHRACHETDP1HTTALKBH5 | |
| SCHEMBL6901641 | 0.68 | KCNH2 (0.41) | TSHRTDP1CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL3127305 | 0.68 | TSHR (0.53) | TSHRACHETDP1HTTALKBH5 | |
| SCHEMBL29357701 | 0.68 | TSHR (0.53) | TSHRACHETDP1HTTALKBH5 | |
| SCHEMBL4480 | 0.68 | TSHR (0.53) | TSHRACHETDP1HTTALKBH5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8487136-B2 | Method for producing norbornene derivative | NIPPON OIL CORPORATION (JP) | 2013-07-16 | — | — | US | disclosed |
| US-8487136-B2 | Method for producing norbornene derivative | NIPPON OIL CORPORATION (JP) | 2013-07-16 | — | — | US | disclosed |
| US-20100197970-A1 | METHOD FOR PRODUCING NORBORNENE DERIVATIVE | NIPPON OIL CORPORATION (JP) | 2010-08-05 | — | — | US | disclosed |
| US-20100197970-A1 | METHOD FOR PRODUCING NORBORNENE DERIVATIVE | NIPPON OIL CORPORATION (JP) | 2010-08-05 | — | — | US | disclosed |
| WO-2001007449-A1 | PHOSPHINE/PALLADIUM COMPLEX CATALYSTS FOR ARYLATION OF OLEFINS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2001-02-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197970-A1 | METHOD FOR PRODUCING NORBORNENE DERIVATIVE | NR0B2, IGF1R, CPNE4 | TSHR 837/4885ACHE 3536/4885TDP1 2451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.