Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 11/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5866781 | 0.81 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL5866731 | 0.80 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL5866851 | 0.78 | CRHR1 (0.40) | CRHR1 | |
| SCHEMBL7480702 | 0.76 | CRHR1 (0.52) | CRHR1 | |
| SCHEMBL8202018 | 0.71 | CRHR1 (0.56) | CRHR1 | |
| SCHEMBL20733330 | 0.71 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL7830712 | 0.70 | CRHR1 (0.45) | CRHR1 | |
| SCHEMBL7945728 | 0.70 | CRHR1 (0.37) | CRHR1 | |
| SCHEMBL8194048 | 0.70 | CRHR1 (0.52) | CRHR1 | |
| SCHEMBL7019686 | 0.68 | CRHR1 (0.39) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124300-A | Aryloxy- and arylthio- fused pyridines and pyrimidines and derivatives | DUPONT PHARMACEUTICALS (US) | 2000-09-26 | — | — | US | claimed |
| US-6258809-B1 | NERVOUS SYSTEM DISORDERS, ANTIDEPRESSANTS AND PSYCHIATRY | DUPONT PHARMACEUTICALS COMPANY | 2001-07-10 | — | — | US | disclosed |
| US-6124300-A | Aryloxy- and arylthio- fused pyridines and pyrimidines and derivatives | DUPONT PHARMACEUTICALS (US) | 2000-09-26 | — | — | US | disclosed |