Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KLK7 | P49862 | 2/20 | 0.50 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.49 |
| ▸ | CPB1 | P15086 | 1/20 | 0.49 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6367781 | 0.95 | KLK7 (0.52) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL6363676 | 0.95 | KLK7 (0.52) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL6757854 | 0.90 | MAPT (0.59) | MAPTKLK7KLK5FOLH1CPB1 | |
| SCHEMBL7946189 | 0.85 | KLK7 (0.60) | MAPTKLK7KLK5FOLH1ITGB3 | |
| SCHEMBL7949794 | 0.83 | CTSK (0.45) | MAPTKLK7KLK5CTSKPPARA | |
| SCHEMBL7944746 | 0.83 | CTSK (0.45) | MAPTKLK7KLK5CTSKPPARA | |
| SCHEMBL2334326 | 0.83 | MAPT (0.68) | MAPTKLK7KLK5FOLH1CPB1 | |
| SCHEMBL2334319 | 0.83 | MAPT (0.68) | MAPTKLK7KLK5FOLH1CPB1 | |
| SCHEMBL3210903 | 0.83 | MAPT (0.68) | MAPTKLK7KLK5FOLH1CPB1 | |
| SCHEMBL7944789 | 0.83 | SLC1A3 (0.56) | FOLH1CPB1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248866-B1 | MULTISTEP PROCESS FOR PRODUCTION OF PROTECTED HYPUSINE STARTING FROM PROTECTED, ESTERIFIED LYSINE | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2001-06-19 | — | — | US | disclosed |