Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 9/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.62 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.60 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.60 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.60 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.60 |
| ▸ | SRC | P12931 | 2/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PLG | P00747 | 1/20 | 0.55 |
| ▸ | PLAU | P00749 | 1/20 | 0.55 |
| ▸ | PLAT | P00750 | 1/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | KIT | P10721 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9322590 | 0.89 | P2RX1 (0.73) | RXFP1MAPTP2RX1SLC2A1P2RX4 | |
| SCHEMBL3034522 | 0.84 | MAPT (0.72) | RXFP1MAPTP2RX1KCNK3LMNA | |
| SCHEMBL3036039 | 0.83 | MAPT (0.70) | RXFP1MAPTP2RX1KCNK3LMNA | |
| SCHEMBL6575251 | 0.82 | PLAU (0.64) | MAPTSRCPLGPLAUPLAT | |
| SCHEMBL3455275 | 0.81 | PLAU (0.71) | RXFP1MAPTP2RX1KCNK3LMNA | |
| SCHEMBL15528949 | 0.81 | RXFP1 (1.00) | RXFP1 | |
| SCHEMBL24141032 | 0.80 | MAPT (0.84) | RXFP1MAPTP2RX1KCNK3LMNA | |
| SCHEMBL4286068 | 0.79 | MAPT (0.94) | RXFP1MAPTP2RX1KCNK3LMNA | |
| SCHEMBL23447711 | 0.79 | MAPT (0.82) | RXFP1MAPTP2RX1KCNK3LMNA | |
| SCHEMBL8484998 | 0.79 | SRC (0.58) | MAPTSRCLMNAPLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6252104-B1 | 3,6-DISUBSTITUTED-2-OXYNAPHTHALENE DERIVATIVES; RAW MATERIALS FOR SYNTHESIS OF SUCH MATERIALS AS DYES, PIGMENTS, PHOTOSENSITIVE MATERIALS | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2001-06-26 | — | — | US | disclosed |
| EP-0765858-B1 | NAPHTHOL DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | UENO SEIYAKU OYO KENKYUJO KK (JP) | 1999-12-22 | — | — | EP | disclosed |
| US-5847233-A | Naphthol derivatives and process for producing the same | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1998-12-08 | — | — | US | disclosed |
| US-5786523-A | Naphthol derivatives and process for producing the same | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1998-07-28 | — | — | US | disclosed |
| EP-0765858-A1 | NAPHTHOL DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1997-04-02 | — | — | EP | disclosed |