SCHEMBL6575251

SCHEMBL6575251

O=C(Nc1ccccc1)c1ccc2cc(O)c(C(=O)Nc3ccccc3)cc2c1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 4/20 0.64
PLG P00747 4/20 0.64
F2 P00734 2/20 0.64
PLAT P00750 2/20 0.64
F10 P00742 1/20 0.64
SRC P12931 1/20 0.62
NPC1 O15118 5/20 0.61
RAB9A P51151 5/20 0.61
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
KLK1 P06870 3/20 0.61
POLB P06746 2/20 0.61
KLKB1 P03952 1/20 0.61
PRSS1 P07477 1/20 0.61
DEGS1 O15121 1/20 0.60
CASP3 P42574 1/20 0.58
SENP7 Q9BQF6 1/20 0.58
SENP6 Q9GZR1 1/20 0.58
KLK6 Q92876 2/20 0.57
KDM4E B2RXH2 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3925183 0.93 PLG (0.62) PLAUPLGF2PLATF10
SCHEMBL3914853 0.93 PLAU (0.62) PLAUPLGF2PLATF10
SCHEMBL6936149 0.92 PLAU (0.56) PLAUPLGF2PLATF10
SCHEMBL6937149 0.92 PLAU (0.56) PLAUPLGF2PLATF10
SCHEMBL8480342 0.92 PLAU (0.62) PLAUPLGF2PLATF10
Hydrochloric Acid SCHEMBL3922499 0.92 PLG (0.61) PLAUPLGF2PLATF10
Hydrochloric Acid SCHEMBL3922301 0.92 PLAU (0.61) PLAUPLGF2PLATF10
SCHEMBL8479137 0.91 PLG (0.62) PLAUPLGF2PLATF10
SCHEMBL8481738 0.91 PLG (0.62) PLAUPLGF2PLATF10
SCHEMBL6937242 0.90 PLG (0.63) PLAUPLGF2PLATF10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8470054-B2 Azo compound, azo pigment, pigment dispersion, coloring composition, color filter, ink for inkjet recording, and printing ink FUJIFILM CORPORATION (JP) 2013-06-25 US disclosed
US-8470054-B2 Azo compound, azo pigment, pigment dispersion, coloring composition, color filter, ink for inkjet recording, and printing ink FUJIFILM CORPORATION (JP) 2013-06-25 US disclosed
US-8454710-B2 Process for producing azo compounds, pigment dispersion, coloring composition, ink for inkjet recording, coloring composition for color filter, and color filter FUJIFILM CORPORATION (JP) 2013-06-04 US disclosed
US-20130036938-A1 AZO COMPOUND, AZO PIGMENT, PIGMENT DISPERSION, COLORING COMPOSITION, COLOR FILTER, INK FOR INKJET RECORDING, AND PRINTING INK FUJIFILM CORPORATION (JP) 2013-02-14 US disclosed
US-20130036938-A1 AZO COMPOUND, AZO PIGMENT, PIGMENT DISPERSION, COLORING COMPOSITION, COLOR FILTER, INK FOR INKJET RECORDING, AND PRINTING INK FUJIFILM CORPORATION (JP) 2013-02-14 US disclosed
US-20120328984-A1 PROCESS FOR PRODUCING AZO COMPOUNDS, PIGMENT DISPERSION, COLORING COMPOSITION, INK FOR INKJET RECORDING, COLORING COMPOSITION FOR COLOR FILTER, AND COLOR FILTER FUJIFILM CORPORATION (JP) 2012-12-27 US disclosed
WO-2011087147-A1 PROCESS FOR PRODUCING AZO COMPOUNDS, PIGMENT DISPERSION, COLORING COMPOSITION, INK FOR INKJET RECORDING, COLORING COMPOSITION FOR COLOR FILTER, AND COLOR FILTER FUJIFILM CORPORATION (JP) 2011-07-21 WO disclosed
EP-0881267-B1 AZO COMPOUNDS AND PROCESS FOR PREPARING THE SAME UENO SEIYAKU OYO KENKYUJO KK (JP) 2004-04-28 EP disclosed
EP-0882767-B1 BISAZO COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF UENO SEIYAKU OYO KENKYUJO KK (JP) 2003-04-16 EP disclosed
US-6548703-B1 Toning agent KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 2003-04-15 US disclosed
US-6252104-B1 3,6-DISUBSTITUTED-2-OXYNAPHTHALENE DERIVATIVES; RAW MATERIALS FOR SYNTHESIS OF SUCH MATERIALS AS DYES, PIGMENTS, PHOTOSENSITIVE MATERIALS KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 2001-06-26 US disclosed
EP-1043364-A1 TONING AGENT KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 2000-10-11 EP disclosed
EP-0765858-B1 NAPHTHOL DERIVATIVES AND PROCESS FOR PRODUCING THE SAME UENO SEIYAKU OYO KENKYUJO KK (JP) 1999-12-22 EP disclosed
US-5973126-A REACTING A 2-HYDROXYNAPHTHALENE-3,6-DICARBOXYLIC ACID, AN AMIDE, OR AN ESTER THEREOF OR DERIVATIVES WITH A DIAZOTIZED AROMATIC PRIMARY AMINE; WATER RESISTANCE, CHEMICAL RESISTANCE AND SOLVENT RESISTANCE. KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1999-10-26 US disclosed
US-5965715-A Bisazo compounds and process for the preparation thereof KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1999-10-12 US disclosed
EP-0882767-A1 BISAZO COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1998-12-09 EP disclosed
US-5847233-A Naphthol derivatives and process for producing the same KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1998-12-08 US disclosed
EP-0881267-A1 AZO COMPOUNDS AND PROCESS FOR PREPARING THE SAME Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1998-12-02 EP disclosed
US-5786523-A Naphthol derivatives and process for producing the same KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1998-07-28 US disclosed
EP-0765858-A1 NAPHTHOL DERIVATIVES AND PROCESS FOR PRODUCING THE SAME KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1997-04-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130036938-A1 AZO COMPOUND, AZO PIGMENT, PIGMENT DISPERSION, COLORING COMPOSITION, COLOR FILTER, INK FOR INKJET RECORDING, AND PRINTING INK RB1, CRY1, TYR PLAU 4456/4885PLG 3954/4885F2 1184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.