Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 2/20 | 0.73 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.67 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.67 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.67 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.67 |
| ▸ | MAOB | P27338 | 1/20 | 0.66 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 10/20 | 0.62 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | TNF | P01375 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | POLA1 | P09884 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3497353 | 0.89 | P2RX1 (0.72) | P2RX1P2RX4P2RX7TMPRSS4MEN1 | |
| SCHEMBL7947175 | 0.89 | RXFP1 (0.69) | P2RX1SLC2A1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL12368137 | 0.86 | NPC1 (0.68) | P2RX1P2RX4P2RX7TMPRSS4AKR1C3 | |
| Salfluverine SCHEMBL2700016 | 0.85 | P2RX1 (1.00) | P2RX1SLC2A1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL27652617 | 0.82 | RXFP1 (0.88) | P2RX1P2RX4P2RX7MAOBPTGS1 | |
| SCHEMBL10863807 | 0.82 | RAB9A (0.64) | MAOBAKR1C3MAPTMEN1HTT | |
| SCHEMBL11070985 | 0.81 | SRC (0.83) | AKR1C3MAPTMEN1HTTKMT2A | |
| SCHEMBL29890853 | 0.81 | MEN1 (0.77) | TMPRSS4MAPTMEN1HTTKMT2A | |
| SCHEMBL57970 | 0.81 | MEN1 (0.77) | TMPRSS4MAPTMEN1HTTKMT2A | |
| SCHEMBL30084384 | 0.81 | MEN1 (0.77) | TMPRSS4MAPTMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989498-B2 | Immunosuppressants; autoimmune disease; organs transplantation; antiinflammatory agents; viricides; antiproliferative agents; antitumor, anticancer agents | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-08-02 | — | — | US | disclosed |
| US-7989498-B2 | Immunosuppressants; autoimmune disease; organs transplantation; antiinflammatory agents; viricides; antiproliferative agents; antitumor, anticancer agents | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-08-02 | — | — | US | disclosed |
| US-7915255-B2 | Metabolism-modulating agents and uses therefor | VERVA PHARMACEUTICALS PTY LTD (AU) | 2011-03-29 | — | — | US | disclosed |
| US-7915255-B2 | Metabolism-modulating agents and uses therefor | VERVA PHARMACEUTICALS PTY LTD (AU) | 2011-03-29 | — | — | US | disclosed |
| EP-0322586-B1 | Photo-receptor for electrophotography | KONISHIROKU PHOTO IND (JP) | 1994-11-02 | — | — | EP | disclosed |
| EP-0356246-B1 | Photoreceptor | KONISHIROKU PHOTO IND (JP) | 1994-02-16 | — | — | EP | disclosed |
| US-4939058-A | Durability | KONICA CORPORATION (JP) | 1990-07-03 | — | — | US | disclosed |
| EP-0356246-A2 | Photoreceptor | KONICA CORPORATION (JP) | 1990-02-28 | — | — | EP | disclosed |
| EP-0322586-A2 | Photo-receptor for electrophotography | KONICA CORPORATION (JP) | 1989-07-05 | — | — | EP | disclosed |
| US-4631242-A | ELECTROCONDUCTIVE SUPPORTS | MITSUBISHI PAPER MILLS, LTD. (JP) | 1986-12-23 | — | — | US | disclosed |