Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956395 | 0.85 | MEN1 (0.38) | MEN1KMT2AHCRTR1GAAMAPK1 | |
| SCHEMBL7947325 | 0.79 | PDE4A (0.40) | MEN1KMT2AHCRTR1GAAMAPK1 | |
| SCHEMBL7961302 | 0.79 | KDM4E (0.37) | MEN1KMT2AHCRTR1GAAALDH1A1 | |
| SCHEMBL7956181 | 0.78 | ALDH1A1 (0.38) | ALDH1A1ACHE | |
| SCHEMBL7956396 | 0.76 | PDE4A (0.39) | MEN1KMT2AHCRTR1GAAMAPK1 | |
| SCHEMBL7961444 | 0.75 | MEN1 (0.35) | MEN1KMT2AALDH1A1ACHE | |
| SCHEMBL7958676 | 0.72 | KMT2A (0.41) | MEN1KMT2AHCRTR1CYP2C9POLB | |
| SCHEMBL6993970 | 0.71 | KCNH2 (0.38) | ALDH1A1ACHE | |
| SCHEMBL7961310 | 0.71 | KDM4E (0.37) | MEN1KMT2AHCRTR1GAAALDH1A1 | |
| SCHEMBL6991711 | 0.71 | HRH1 (0.47) | MEN1KMT2AHCRTR1GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329392-B1 | ANTIALLERGENS | AVENTIS PHARMACEUTICALS, INC. | 2001-12-11 | — | — | US | disclosed |
| EP-0777666-B1 | SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMA INC (US) | 1999-03-03 | — | — | EP | disclosed |
| WO-1996006094-A1 | NOVEL SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1996-02-29 | — | — | WO | disclosed |