Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956181 | 0.90 | ALDH1A1 (0.38) | ACHEHTTKDM4EALDH1A1KCNH2 | |
| SCHEMBL7956395 | 0.85 | MEN1 (0.38) | MEN1KMT2AACHEALDH1A1 | |
| SCHEMBL7961302 | 0.85 | KDM4E (0.37) | MEN1KMT2AHTTKDM4EALDH1A1 | |
| SCHEMBL7961451 | 0.82 | MEN1 (0.37) | MEN1KMT2ANPC1ACHEHTT | |
| SCHEMBL6993970 | 0.82 | KCNH2 (0.38) | ACHEHTTKDM4EALDH1A1KCNH2 | |
| SCHEMBL7947321 | 0.75 | MEN1 (0.37) | MEN1KMT2AACHEALDH1A1 | |
| SCHEMBL7961053 | 0.74 | MEN1 (0.42) | MEN1KMT2ANPC1ACHEHTT | |
| SCHEMBL7956188 | 0.73 | ALDH1A1 (0.38) | MEN1KMT2AACHEHTTKDM4E | |
| SCHEMBL7958676 | 0.73 | KMT2A (0.41) | MEN1KMT2AKCNH2 | |
| SCHEMBL7961447 | 0.73 | HRH1 (0.38) | MEN1KMT2ANPC1ACHEHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329392-B1 | ANTIALLERGENS | AVENTIS PHARMACEUTICALS, INC. | 2001-12-11 | — | — | US | disclosed |
| EP-0777666-B1 | SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMA INC (US) | 1999-03-03 | — | — | EP | disclosed |
| EP-0777666-A1 | NOVEL SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996006094-A1 | NOVEL SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1996-02-29 | — | — | WO | disclosed |