Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14730686 | 0.76 | MAPT (0.41) | SIRT2MEN1ALDH1A1GAAKMT2A | |
| SCHEMBL15718645 | 0.76 | SIRT2 (0.36) | SIRT2ALDH1A1GAACRHBPCRHR2 | |
| SCHEMBL3645280 | 0.74 | ALDH1A1 (0.38) | MEN1ALDH1A1GAAKMT2A | |
| SCHEMBL5100980 | 0.73 | KDM4E (0.46) | MEN1ALDH1A1KMT2A | |
| SCHEMBL19156271 | 0.73 | MAPT (0.41) | SIRT2MEN1ALDH1A1GAAKMT2A | |
| SCHEMBL25382722 | 0.73 | TAS2R38 (0.36) | SIRT2MEN1ALDH1A1GAAKMT2A | |
| SCHEMBL18639126 | 0.73 | KDM4E (0.31) | ALDH1A1GAA | |
| SCHEMBL15832541 | 0.71 | — | — | |
| SCHEMBL13950504 | 0.71 | SMN1; SMN2 (0.39) | MEN1ALDH1A1KMT2A | |
| SCHEMBL12274479 | 0.71 | NR4A2 (0.39) | MEN1ALDH1A1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2310013-B1 | BICYCLIC TRIAZOLE DERIVATIVES FOR TREATING TUMORS | MERCK PATENT GMBH (DE) | 2017-08-23 | — | — | EP | disclosed |
| WO-2010030500-A1 | AZA-BENZIMIDAZOLONE CHYMASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-03-18 | — | — | WO | disclosed |