Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 8/20 | 0.44 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 5/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3220703 | 0.89 | HTR6 (0.44) | HTR6KDM2B | |
| SCHEMBL3223782 | 0.89 | HTR6 (0.47) | METHTR6KDM2B | |
| SCHEMBL3214560 | 0.89 | HTR6 (0.50) | METHTR6DRD3 | |
| SCHEMBL3222864 | 0.89 | MET (0.48) | METHTR6KDM2B | |
| SCHEMBL3216915 | 0.87 | KDM2B (0.41) | HTR6ADCY5KDM2B | |
| SCHEMBL3218158 | 0.87 | HTR6 (0.45) | HTR6KDM2B | |
| SCHEMBL3214442 | 0.87 | HTR6 (0.46) | METHTR6CHRM4 | |
| SCHEMBL3215703 | 0.86 | HTR6 (0.54) | METHTR6DRD3 | |
| SCHEMBL3218478 | 0.84 | POLB (0.46) | HTR6KDM2BCHRM1 | |
| SCHEMBL3221961 | 0.82 | HTR6 (0.45) | HTR6KDM2BCHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010021797-A1 | CONDENSED HETEROCYCLIC COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-02-25 | — | — | WO | disclosed |