Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HCRTR2 | O43614 | 9/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7000377 | 0.94 | MEN1 (0.41) | MEN1KMT2AHCRTR2HCRTR1L3MBTL1 | |
| SCHEMBL6997660 | 0.83 | MAPK1 (0.39) | MEN1KMT2AHCRTR1PDE4APDE4B | |
| SCHEMBL7985088 | 0.78 | MAPK1 (0.38) | MEN1KMT2AHCRTR1PDE4APDE4B | |
| SCHEMBL7954875 | 0.77 | KMT2A (0.59) | MEN1KMT2AHCRTR2HCRTR1L3MBTL1 | |
| SCHEMBL6733910 | 0.77 | KMT2A (0.62) | MEN1KMT2AHCRTR2HCRTR1L3MBTL1 | |
| SCHEMBL6997070 | 0.77 | KMT2A (0.37) | MEN1KMT2AHCRTR2HCRTR1ALDH1A1 | |
| SCHEMBL7954267 | 0.76 | KMT2A (0.54) | MEN1KMT2AHCRTR2HCRTR1L3MBTL1 | |
| SCHEMBL7971732 | 0.74 | HRH1 (0.38) | MEN1KMT2AHCRTR1KDM4EGAA | |
| SCHEMBL7002664 | 0.74 | HRH1 (0.40) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL7961305 | 0.73 | KDM4E (0.39) | MEN1KMT2APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329392-B1 | ANTIALLERGENS | AVENTIS PHARMACEUTICALS, INC. | 2001-12-11 | — | — | US | disclosed |
| EP-0777666-B1 | SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMA INC (US) | 1999-03-03 | — | — | EP | disclosed |
| EP-0777666-A1 | NOVEL SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996006094-A1 | NOVEL SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1996-02-29 | — | — | WO | disclosed |