Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6999822 | 0.92 | KMT2A (0.51) | KMT2AMEN1L3MBTL1HCRTR1HCRTR2 | |
| SCHEMBL6733910 | 0.84 | KMT2A (0.62) | KMT2AMEN1L3MBTL1HCRTR1HCRTR2 | |
| SCHEMBL7954267 | 0.83 | KMT2A (0.54) | KMT2AMEN1L3MBTL1HCRTR1HCRTR2 | |
| SCHEMBL27378900 | 0.80 | KMT2A (0.50) | KMT2AMEN1L3MBTL1HCRTR1HCRTR2 | |
| SCHEMBL19585933 | 0.80 | KMT2A (0.57) | KMT2AMEN1L3MBTL1HCRTR1HCRTR2 | |
| SCHEMBL7046375 | 0.79 | KMT2A (0.68) | KMT2AMEN1L3MBTL1HCRTR1HCRTR2 | |
| SCHEMBL7947397 | 0.77 | MEN1 (0.48) | KMT2AMEN1L3MBTL1HCRTR1HCRTR2 | |
| SCHEMBL6999204 | 0.77 | MAPK1 (0.46) | KMT2AMEN1HCRTR1POLBCYP2C9 | |
| SCHEMBL9726979 | 0.75 | KMT2A (1.00) | KMT2AMEN1L3MBTL1HCRTR1HCRTR2 | |
| SCHEMBL6733707 | 0.75 | KMT2A (0.54) | KMT2AMEN1L3MBTL1HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329392-B1 | ANTIALLERGENS | AVENTIS PHARMACEUTICALS, INC. | 2001-12-11 | — | — | US | disclosed |
| CN-1067385-C | Novel substituted piperidines useful for the treatment of allergic diseases | MERRELL DOW PHARMA (US) | 2001-06-20 | — | — | CN | disclosed |
| EP-0777666-B1 | SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMA INC (US) | 1999-03-03 | — | — | EP | disclosed |
| CN-1158612-A | Novel substituted piperidines for the treatment of allergic diseases | MERRELL DOW PHARMA (US) | 1997-09-03 | — | — | CN | disclosed |
| EP-0777666-A1 | NOVEL SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996006094-A1 | NOVEL SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1996-02-29 | — | — | WO | disclosed |