Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 4/20 | 0.43 |
| ▸ | TACR2 | P21452 | 7/20 | 0.42 |
| ▸ | TACR1 | P25103 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | TACR3 | P29371 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947479 | 0.89 | CCR8 (0.52) | CCR8KCNH2HRH1TACR2TACR1 | |
| SCHEMBL7961464 | 0.86 | HRH1 (0.50) | HRH1TACR2TACR1TACR3 | |
| SCHEMBL7958307 | 0.81 | TACR2 (0.55) | HRH1TACR2TACR1TACR3 | |
| SCHEMBL7955900 | 0.80 | HRH1 (0.52) | HRH1TACR2TACR1SMN1; SMN2TACR3 | |
| SCHEMBL8814905 | 0.79 | RAB9A (0.40) | CCR8KCNH2KDM4ENPC1RAB9A | |
| SCHEMBL8303632 | 0.76 | TACR1 (0.56) | HRH1TACR2TACR1TACR3 | |
| SCHEMBL8883701 | 0.75 | TACR2 (0.55) | HRH1TACR2TACR1TACR3 | |
| SCHEMBL7947283 | 0.75 | TACR2 (0.57) | HRH1TACR2TACR1TACR3 | |
| SCHEMBL8356003 | 0.75 | TACR2 (0.48) | HRH1TACR2TACR1TACR3 | |
| SCHEMBL7956025 | 0.74 | HRH1 (0.52) | HRH1TACR2TACR1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329392-B1 | ANTIALLERGENS | AVENTIS PHARMACEUTICALS, INC. | 2001-12-11 | — | — | US | disclosed |
| EP-0777666-B1 | SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMA INC (US) | 1999-03-03 | — | — | EP | disclosed |
| WO-1996006094-A1 | NOVEL SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1996-02-29 | — | — | WO | disclosed |