Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 6/20 | 0.56 |
| ▸ | TACR2 | P21452 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 4/20 | 0.43 |
| ▸ | TACR3 | P29371 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305246 | 0.89 | TACR2 (0.59) | TACR1TACR2HTTHRH1TACR3 | |
| SCHEMBL7958307 | 0.87 | TACR2 (0.55) | TACR1TACR2HRH1TACR3 | |
| SCHEMBL7961464 | 0.80 | HRH1 (0.50) | TACR1TACR2HRH1TACR3 | |
| SCHEMBL7954948 | 0.78 | TACR2 (0.64) | TACR1TACR2HRH1TACR3 | |
| SCHEMBL7947581 | 0.78 | TACR2 (0.51) | TACR1TACR2HRH1TACR3 | |
| SCHEMBL7955900 | 0.78 | HRH1 (0.52) | TACR1TACR2HRH1TACR3 | |
| SCHEMBL7956210 | 0.77 | ALDH1A1 (0.54) | TACR1TACR2HRH1TACR3 | |
| SCHEMBL7958328 | 0.77 | TACR2 (0.53) | TACR1TACR2HRH1TACR3 | |
| SCHEMBL8885360 | 0.77 | TACR1 (0.45) | TACR1TACR2 | |
| SCHEMBL7958458 | 0.77 | TACR2 (0.51) | TACR1TACR2HRH1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777666-B1 | SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMA INC (US) | 1999-03-03 | — | — | EP | disclosed |