Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 16/20 | 0.45 |
| ▸ | GNRHR | P30968 | 2/20 | 0.41 |
| ▸ | RXRB | P28702 | 5/20 | 0.39 |
| ▸ | RXRG | P48443 | 5/20 | 0.39 |
| ▸ | RARB | P10826 | 3/20 | 0.37 |
| ▸ | RARG | P13631 | 3/20 | 0.37 |
| ▸ | RARA | P10276 | 2/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7931914 | 0.84 | RXRA (0.49) | RXRAGNRHRRXRBRXRGRARB | |
| SCHEMBL7134767 | 0.79 | RXRA (0.40) | RXRAGNRHRMEN1KMT2AKCNH2 | |
| SCHEMBL7947551 | 0.78 | RXRA (0.46) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8854034 | 0.72 | RXRA (0.38) | RXRAGNRHRRXRBRXRGRARB | |
| SCHEMBL2647307 | 0.71 | CYP3A4 (0.48) | MEN1ESR1KMT2ACYP3A4TDP1 | |
| SCHEMBL7929381 | 0.71 | RXRA (0.47) | RXRAGNRHRRXRBRXRGRARB | |
| SCHEMBL3186076 | 0.70 | RARB (0.38) | RXRARXRBRXRGRARBRARG | |
| Bromide SCHEMBL7941365 | 0.70 | RXRA (0.46) | RXRAGNRHRRXRBRXRGRARB | |
| SCHEMBL22001266 | 0.69 | RXRA (0.54) | RXRAGNRHRRXRBRXRGRARB | |
| SCHEMBL3550442 | 0.68 | RXRA (0.41) | RXRAGNRHRRXRBRXRGRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265423-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE EUROPEEN DE BIOPROSPECTIVE-CEB (FR) | 2001-07-24 | — | — | US | disclosed |