Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 4/20 | 0.54 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.54 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.51 |
| ▸ | CHRNB3 | Q05901 | 2/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7957021 | 0.77 | KDM4E (0.58) | TTRNPSR1 | |
| SCHEMBL7962009 | 0.76 | KDM4E (0.60) | TTRNPSR1 | |
| SCHEMBL5734066 | 0.75 | MAPT (0.55) | TTRNPSR1 | |
| SCHEMBL7947523 | 0.74 | MAPT (0.54) | TTRNPSR1 | |
| SCHEMBL7959021 | 0.73 | MAPT (0.50) | TTRNPSR1 | |
| SCHEMBL5733357 | 0.73 | KDM4E (0.63) | TTRNPSR1 | |
| SCHEMBL7957043 | 0.72 | USP2 (0.64) | TTRNPSR1 | |
| SCHEMBL26729833 | 0.71 | CHRNB4 (0.65) | CHRNB4CHRNA3CHRNB1CHRNB2CHRNB3 | |
| SCHEMBL7961699 | 0.71 | SMN1; SMN2 (0.81) | NPSR1 | |
| SCHEMBL12232966 | 0.70 | CHRNB4 (0.68) | CHRNB4CHRNA3CHRNB1CHRNB2CHRNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277872-B1 | ANTIISCHEMIC AGENTS; BRAIN DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 2001-08-21 | — | — | US | disclosed |