Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD5 | P21918 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7957021 | 0.99 | KDM4E (0.58) | KDM4ESMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL5734066 | 0.90 | MAPT (0.55) | KDM4ESMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL5733357 | 0.90 | KDM4E (0.63) | KDM4EKMT2AMEN1LMNAPOLB | |
| SCHEMBL7952011 | 0.85 | KDM4E (0.49) | KDM4ESMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL7957043 | 0.84 | USP2 (0.64) | KDM4EALDH1A1KMT2AMEN1PKM | |
| SCHEMBL7947674 | 0.81 | SMN1; SMN2 (0.53) | KDM4ESMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL14970458 | 0.81 | KDM4E (0.86) | KDM4ESMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL14175879 | 0.81 | TDP1 (0.53) | KDM4ESMN1; SMN2KMT2AMEN1PTPN1 | |
| SCHEMBL7947543 | 0.80 | PTPN1 (0.55) | KDM4ESMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL7012697 | 0.79 | KDM4E (0.84) | KDM4ESMN1; SMN2ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277872-B1 | ANTIISCHEMIC AGENTS; BRAIN DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 2001-08-21 | — | — | US | disclosed |