Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 3/20 | 0.45 |
| ▸ | CES1 | P23141 | 3/20 | 0.45 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.43 |
| ▸ | PPARG | P37231 | 7/20 | 0.43 |
| ▸ | PPARD | Q03181 | 7/20 | 0.43 |
| ▸ | PPARA | Q07869 | 7/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11716770 | 1.00 | KMT2A (0.48) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL9164814 | 1.00 | KMT2A (0.48) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL7614751 | 0.98 | KMT2A (0.45) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL7947728 | 0.86 | KMT2A (0.50) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL9164807 | 0.86 | KMT2A (0.50) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL11716766 | 0.86 | KMT2A (0.50) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL7614748 | 0.84 | KMT2A (0.47) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL28661379 | 0.84 | ALDH1A1 (0.37) | CES2CES1TSHRALDH1A1 | |
| SCHEMBL9157111 | 0.81 | ALDH1A1 (0.50) | TSHRALDH1A1 | |
| SCHEMBL10636366 | 0.78 | KDM4C (0.36) | KMT2ATSHRPTPN1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5004982-A | — | — | None | — | — | JP | disclosed |
| US-6265440-B1 | STOMACH ULCERS | R-TECH UENO, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| JP-H054982-A | PRODUCTION OF INTERMEDIATE FOR PROSTAGLADIN | UENO SEIYAKU OYO KENKYUSHO:KK | 1993-01-14 | — | — | JP | disclosed |
| EP-0472338-A2 | Method of manufacturing prostaglandin intermediate | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1992-02-26 | — | — | EP | disclosed |
| US-4279919-A | HYPOTENSIVE | ROUSSEL UCLAF (FR) | 1981-07-21 | — | — | US | disclosed |
| US-4221809-A | HYPOTENSIVE AGENTS | ROUSSEL UCLAF (FR) | 1980-09-09 | — | — | US | disclosed |