Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 6/20 | 0.40 |
| ▸ | FYN | P06241 | 9/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3198471 | 0.79 | GPR52 (0.62) | GPR52FYNPDE7A | |
| SCHEMBL13489559 | 0.67 | GPR52 (0.65) | GPR52FYNPDE7A | |
| SCHEMBL3218822 | 0.63 | GPR52 (0.67) | GPR52 | |
| SCHEMBL3215801 | 0.62 | GPR52 (0.45) | GPR52 | |
| SCHEMBL3207002 | 0.60 | GPR52 (0.60) | GPR52FYNLIMK1 | |
| SCHEMBL3207357 | 0.59 | GPR52 (0.62) | GPR52FYNPDE7A | |
| SCHEMBL3207171 | 0.59 | GPR52 (0.68) | GPR52FYN | |
| SCHEMBL3319225 | 0.58 | SMN1; SMN2 (0.65) | — | |
| SCHEMBL3206759 | 0.58 | GPR52 (0.63) | GPR52FYNLIMK1 | |
| SCHEMBL12001125 | 0.58 | ACACB (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |