Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3650164 | 0.91 | SMN1; SMN2 (0.56) | SMN1; SMN2HPGDPOLBHTTHSD17B10 | |
| SCHEMBL9667962 | 0.89 | KDM4E (0.62) | SMN1; SMN2HPGDPOLBHTTHSD17B10 | |
| SCHEMBL9717416 | 0.88 | SMN1; SMN2 (0.71) | SMN1; SMN2HPGDPOLBHTTHSD17B10 | |
| SCHEMBL23471362 | 0.88 | CYP4F2 (0.58) | SMN1; SMN2HPGDPOLBHTTHSD17B10 | |
| SCHEMBL1663227 | 0.87 | L3MBTL1 (0.76) | SMN1; SMN2HPGDPOLBHTTKMT2A | |
| SCHEMBL3650167 | 0.87 | HPGD (0.54) | SMN1; SMN2HPGDPOLBHTTHSD17B10 | |
| SCHEMBL7370988 | 0.87 | HPGD (0.54) | SMN1; SMN2HPGDPOLBHTTHSD17B10 | |
| SCHEMBL842631 | 0.87 | NPC1 (0.68) | SMN1; SMN2HPGDPOLBHTTHSD17B10 | |
| SCHEMBL19634287 | 0.87 | NPC1 (0.55) | SMN1; SMN2HPGDPOLBHTTHSD17B10 | |
| SCHEMBL29583694 | 0.87 | GAA (0.62) | SMN1; SMN2HPGDPOLBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4687834-A | Polyester imides and method for producing same | HULS AKTIENGESELLSCHAFT (DE) | 1987-08-18 | — | — | US | claimed |
| JP-3229751-A | — | — | None | — | — | JP | disclosed |
| EP-4299656-A1 | PREPARATION OF PROPOXYLATED BENZENEDICARBOXYLIC ACID AMIDES AND CORRESPONDING POLYURETHANE FOAM | Evonik Operations GmbH (DE) | 2024-01-03 | — | — | EP | disclosed |
| US-9828332-B2 | Non-peptide BDNF neurotrophin mimetics | PharmatorophiX, Inc. (US) | 2017-11-28 | — | — | US | disclosed |
| EP-2131239-B1 | Processing liquid for lithographic printing plate development and method of producing lithographic printing plates | FUJIFILM CORP (JP) | 2016-03-23 | — | — | EP | disclosed |
| US-20160023990-A1 | NON-PEPTIDE BDNF NEUROTROPHIN MIMETICS | PHARMATROPHIX, INC. | 2016-01-28 | — | — | US | disclosed |
| US-20140296343-A1 | NON-PEPTIDE BDNF NEUROTROPHIN MIMETICS | PHARMATROPHIX, INC. | 2014-10-02 | — | — | US | disclosed |
| US-20120004310-A1 | NON-PEPTIDE BDNF NEUROTROPHIN MIMETICS | PHARMATROPHIX, INC. | 2012-01-05 | — | — | US | disclosed |
| US-20110146516-A1 | METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE | FUJIFILM CORPORATION (JP) | 2011-06-23 | — | — | US | disclosed |
| US-20110146516-A1 | METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE | FUJIFILM CORPORATION (JP) | 2011-06-23 | — | — | US | disclosed |
| US-4923536-A | Explosives and propellant compositions containing a polyurethane polyacetal elastomer binder and method for the preparation thereof | OLIN CORPORATION (US) | 1990-05-08 | — | — | US | disclosed |
| US-4808689-A | BINDER FOR HIGH ENERGY EXPLOSIVES, PROPELLANTS | OLIN CORPORATION (US) | 1989-02-28 | — | — | US | disclosed |
| US-4739032-A | Aromatic oligomers and resins | IMPERIAL CHEMICAL INDUSTRIES PLC | 1988-04-19 | — | — | US | disclosed |
| US-4687834-A | Polyester imides and method for producing same | HULS AKTIENGESELLSCHAFT (DE) | 1987-08-18 | — | — | US | disclosed |
| US-4673725-A | WITH PENDANT HYDROXY, ESTER, OR CARBOXY GROUPS TO COMBINE WITH AROMATIC AMINE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-06-16 | — | — | US | disclosed |
| EP-0222980-A2 | Polyester imide and process for its preparation | HÜLS AKTIENGESELLSCHAFT (DE) | 1987-05-27 | — | — | EP | disclosed |
| US-4599373-A | ACRYLATED AROMATIC-ALDEHYDE RESINS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-07-08 | — | — | US | disclosed |
| US-4530992-A | Reacting an aromatic compound, aldehyde and carboxylic acid | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-07-23 | — | — | US | disclosed |
| EP-0112650-A2 | Aromatic oligomers and resins | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-07-04 | — | — | EP | disclosed |
| US-4174455-A | CHAIN EXTENSION, CROSSLINKING AND/OR CURINF OF POLYUREAS, POLYURETHANES, AND EPOXY RESINS | CIBA-GEIGY CORPORATION (US) | 1979-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160023990-A1 | NON-PEPTIDE BDNF NEUROTROPHIN MIMETICS | BDNF, NTRK2, NGF | SMN1; SMN2 34/4885HPGD 3575/4885POLB 3850/4885 |
| US-20120004310-A1 | NON-PEPTIDE BDNF NEUROTROPHIN MIMETICS | BDNF, NTRK2, NGF | SMN1; SMN2 34/4885HPGD 3575/4885POLB 3850/4885 |
| US-20140296343-A1 | NON-PEPTIDE BDNF NEUROTROPHIN MIMETICS | BDNF, NTRK2, NGF | SMN1; SMN2 34/4885HPGD 3575/4885POLB 3850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.