Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 9/20 | 0.41 |
| ▸ | CDC25B | P30305 | 5/20 | 0.41 |
| ▸ | SELP | P16109 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7948003 | 0.92 | NT5E (0.62) | NT5EPTPN1CDC25BSELPPTPN2 | |
| SCHEMBL8317395 | 0.92 | NT5E (0.62) | NT5EPTPN1CDC25BSELPPTPN2 | |
| SCHEMBL7955496 | 0.90 | NT5E (0.60) | NT5EPTPN1CDC25BSELPPTPN2 | |
| SCHEMBL7955495 | 0.90 | NT5E (0.60) | NT5EPTPN1CDC25BSELPPTPN2 | |
| SCHEMBL7948307 | 0.87 | NT5E (0.64) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL7948306 | 0.87 | NT5E (0.64) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL16348277 | 0.85 | NT5E (0.55) | NT5EPTPN1CDC25BSELPPTPN2 | |
| SCHEMBL22073057 | 0.85 | NT5E (0.49) | NT5EPTPN1CDC25BPTPN2LMNA | |
| SCHEMBL22073764 | 0.83 | NT5E (0.48) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL7955866 | 0.83 | NT5E (0.61) | NT5EPTPN1CDC25BPTPN2PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271342-B1 | SERUM STABILITY; FOR TUMOR THERAPY | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-07 | — | — | US | disclosed |