Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.60 |
| ▸ | SELP | P16109 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.37 |
| ▸ | CDC25B | P30305 | 5/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | FGF2 | P09038 | 1/20 | 0.36 |
| ▸ | MDK | P21741 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7955496 | 1.00 | NT5E (0.60) | NT5ESELPCA1CA2CA9 | |
| SCHEMBL7962171 | 0.92 | NT5E (0.60) | NT5ECA1CA2CA9PTPN1 | |
| SCHEMBL7962172 | 0.92 | NT5E (0.60) | NT5ECA1CA2CA9PTPN1 | |
| SCHEMBL7948006 | 0.90 | NT5E (0.66) | NT5ESELPPTPN1CDC25BPTPN2 | |
| SCHEMBL8317395 | 0.85 | NT5E (0.62) | NT5ESELPPTPN1CDC25BPTPN2 | |
| SCHEMBL7948003 | 0.85 | NT5E (0.62) | NT5ESELPPTPN1CDC25BPTPN2 | |
| SCHEMBL7948306 | 0.81 | NT5E (0.64) | NT5ECA1CA2CA9PTPN1 | |
| SCHEMBL7948307 | 0.81 | NT5E (0.64) | NT5ECA1CA2CA9PTPN1 | |
| SCHEMBL30074377 | 0.80 | NT5E (0.49) | NT5ECYP2D6ALDH1A1MAPK1 | |
| SCHEMBL16348277 | 0.79 | NT5E (0.55) | NT5ESELPPTPN1CDC25BPTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271342-B1 | SERUM STABILITY; FOR TUMOR THERAPY | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-07 | — | — | US | disclosed |
| EP-0819135-B1 | SUGAR-MODIFIED CYTOSTATICS | BAYER AG (DE) | 1999-11-17 | — | — | EP | disclosed |