Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7941788 | 0.90 | NPSR1 (0.48) | MAPTLMNAPOLBALDH1A1NPSR1 | |
| SCHEMBL7948105 | 0.87 | NPSR1 (0.53) | MAPTLMNAPOLBALDH1A1NPSR1 | |
| SCHEMBL7951730 | 0.86 | NPSR1 (0.40) | LMNAPOLBALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL7953545 | 0.86 | KMT2A (0.43) | POLBALDH1A1NPSR1SMN1; SMN2KMT2A | |
| SCHEMBL7949769 | 0.85 | L3MBTL1 (0.51) | MAPTALDH1A1NPSR1SMN1; SMN2MEN1 | |
| SCHEMBL7953611 | 0.79 | NPSR1 (0.67) | MAPTLMNAPOLBALDH1A1NPSR1 | |
| SCHEMBL7951736 | 0.78 | NPSR1 (0.44) | MAPTLMNAPOLBNPSR1SMN1; SMN2 | |
| SCHEMBL7948165 | 0.76 | NPSR1 (0.51) | LMNAPOLBALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL7949206 | 0.76 | NPSR1 (0.53) | POLBALDH1A1NPSR1SMN1; SMN2KMT2A | |
| SCHEMBL7949082 | 0.74 | MAPT (0.43) | MAPTLMNAPOLBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255517-B1 | 6-SULFONYLOXYISOPROPENYL-M-CRESOL AND ESTERS | Zee, Ok Pyo (KR) | 2001-07-03 | — | — | US | disclosed |