Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 9/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1604919 | 0.88 | CYP11B2 (0.49) | CYP11B2CYP11B1TBXAS1NPSR1MAOA | |
| SCHEMBL1605952 | 0.86 | CYP11B2 (0.50) | CYP11B2CYP11B1GRM2PTGES2TBXAS1 | |
| SCHEMBL1606033 | 0.83 | TP53 (0.47) | CYP11B2CYP11B1GRM2PTGES2TBXAS1 | |
| SCHEMBL1604835 | 0.82 | GRIN1 (0.48) | CYP11B2CYP11B1GRIN1GRIN2BNPSR1 | |
| SCHEMBL28107204 | 0.81 | CYP11B2 (0.59) | CYP11B2CYP11B1PTGES2TBXAS1KDM4E | |
| Hydrochloric Acid SCHEMBL30385478 | 0.81 | GRIN1 (0.47) | CYP11B2CYP11B1GRIN1GRIN2BNPSR1 | |
| Hydrochloric Acid SCHEMBL1606192 | 0.81 | GRIN1 (0.47) | CYP11B2CYP11B1GRIN1GRIN2BNPSR1 | |
| SCHEMBL1605597 | 0.78 | PTGES2 (0.49) | CYP11B2PTGES2TBXAS1KDM4E | |
| SCHEMBL27810049 | 0.76 | TBXAS1 (0.53) | CYP11B2CYP11B1GRM2PTGES2TBXAS1 | |
| SCHEMBL1606366 | 0.76 | CYP11B2 (0.63) | CYP11B2TBXAS1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009156462-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-12-30 | — | — | WO | disclosed |