Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.50 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7279463 | 0.85 | MAPT (0.55) | MAPTTDP1LMNAHTTSMN1; SMN2 | |
| SCHEMBL29373756 | 0.83 | TSHR (0.55) | MAPTTDP1LMNAHTTPTPN1 | |
| SCHEMBL3369498 | 0.82 | TDP1 (0.50) | MAPTTDP1HTTALDH1A1KLKB1 | |
| SCHEMBL15529212 | 0.81 | ESR1 (0.47) | HNF4AACMSDMAPTTDP1LMNA | |
| SCHEMBL3245100 | 0.81 | TDP1 (0.49) | MAPTTDP1HTTALDH1A1KLKB1 | |
| SCHEMBL9244765 | 0.80 | HNF4A (0.59) | HNF4AACMSDMAPTLMNAHTT | |
| SCHEMBL25232693 | 0.80 | TDP1 (0.47) | MAPTTDP1LMNAHTTTSHR | |
| SCHEMBL8767656 | 0.80 | HNF4A (0.54) | HNF4AACMSDMAPTHTTSMN1; SMN2 | |
| SCHEMBL3365334 | 0.80 | TDP1 (0.47) | MAPTTDP1HTT | |
| SCHEMBL3370741 | 0.80 | TDP1 (0.47) | MAPTTDP1HTTALDH1A1KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107881188-A | A kind of method that whole-cell catalyst prepares aromatic aldehyde and/or aromatic alcohol | 上海交通大学 | 2018-04-06 | — | — | CN | disclosed |
| US-6261814-B1 | MIXING PURIFIED, BIOLOGICALLY-DERIVED REDUCTASE FROM NOCARDIA SPECIES WITH CARBOXYLIC ACID OR DERIVATIVE; PRODUCTION OF VANILLIN FROM VANILLIC ACID | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2001-07-17 | — | — | US | disclosed |
| WO-1998040472-A2 | CARBOXYLIC ACID REDUCTASE, AND METHODS OF USING SAME | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1998-09-17 | — | — | WO | disclosed |
| US-5795759-A | Carboxylic acid reductase, and methods of using same | THE UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1998-08-18 | — | — | US | disclosed |