SCHEMBL8767656

SCHEMBL8767656

Cc1c(O)ccc(C(=O)O)c1Cc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HNF4A P41235 1/20 0.54
SHBG P04278 1/20 0.50
ACMSD Q8TDX5 1/20 0.48
KDM4E B2RXH2 3/20 0.46
MAPT P10636 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
JAK2 O60674 1/20 0.46
POLB P06746 1/20 0.46
GAA P10253 1/20 0.46
PKM P14618 1/20 0.46
MAPK1 P28482 1/20 0.46
MPI P34949 1/20 0.46
HTT P42858 1/20 0.46
BLM P54132 1/20 0.46
MCL1 Q07820 1/20 0.46
PTPN1 P18031 4/20 0.44
PTPN2 P17706 1/20 0.44
PTPN6 P29350 1/20 0.44
KLKB1 P03952 1/20 0.43
CTSB P07858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9244765 0.84 HNF4A (0.59) HNF4AACMSDKDM4EMAPTSMN1; SMN2
SCHEMBL536885 0.83 HNF4A (0.57) HNF4AACMSDKDM4EMAPTSMN1; SMN2
SCHEMBL26502 0.82 HNF4A (0.53) HNF4AACMSDMAPTGAAPTPN1
SCHEMBL8368640 0.81 HNF4A (0.56) HNF4AACMSDKDM4ESMN1; SMN2HTT
SCHEMBL7948311 0.80 HNF4A (0.50) HNF4AACMSDMAPTSMN1; SMN2MAPK1
SCHEMBL10721869 0.79 HNF4A (0.57) HNF4AACMSDKDM4EMAPTSMN1; SMN2
SCHEMBL27452298 0.79 SHBG (0.51) HNF4ASHBGKDM4EMAPTSMN1; SMN2
SCHEMBL2301655 0.79 CSNK2A1 (0.46) MAPTSMN1; SMN2PKMMCL1KLKB1
SCHEMBL10398688 0.79 HNF4A (0.53) HNF4AACMSDKDM4EMAPTSMN1; SMN2
SCHEMBL7204828 0.78 IDH1 (0.47) HNF4AHTTPTPN1PTPN2PTPN6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102019782-B Thermosensitive recording material and production method thereof RICOH CO LTD 2013-11-06 CN disclosed
CN-102019782-A Thermosensitive recording material and production method thereof RICOH CO LTD 2011-04-20 CN disclosed
EP-0585127-B1 Thermal Recording sheet JUJO PAPER CO LTD (JP) 1997-12-29 EP disclosed
EP-0570186-B1 Thermal recording sheet JUJO PAPER CO LTD (JP) 1997-08-13 EP disclosed
US-5405821-A Containing a 4-hydroxyphenylarylsulfone color developer NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1995-04-11 US disclosed
EP-0570186-A1 Thermal recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1993-11-18 EP disclosed
US-4727162-A COLOR FORMERS FOR HEAT OR PRESSURE RECORDING MATERIAL SHIN NISSO KAKO CO., LTD. (JP) 1988-02-23 US disclosed
US-4695640-A COLOR FORMER FOR RECORDING MATERIALS SHIN NISSO KAKO CO., LTD. (JP) 1987-09-22 US disclosed