Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.54 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.53 |
| ▸ | HSPA8 | P11142 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MTOR | P42345 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8789685 | 1.00 | PNP (0.54) | PNPHSPA5HSPA8MEN1KMT2A | |
| SCHEMBL2185987 | 1.00 | PNP (0.54) | PNPHSPA5HSPA8MEN1KMT2A | |
| SCHEMBL10661591 | 1.00 | PNP (0.54) | PNPHSPA5HSPA8MEN1KMT2A | |
| SCHEMBL10814753 | 1.00 | PNP (0.54) | PNPHSPA5HSPA8MEN1KMT2A | |
| SCHEMBL10496354 | 1.00 | PNP (0.54) | PNPHSPA5HSPA8MEN1KMT2A | |
| SCHEMBL10814776 | 1.00 | PNP (0.54) | PNPHSPA5HSPA8MEN1KMT2A | |
| SCHEMBL132926 | 1.00 | PNP (0.54) | PNPHSPA5HSPA8MEN1KMT2A | |
| SCHEMBL375987 | 1.00 | PNP (0.54) | PNPHSPA5HSPA8MEN1KMT2A | |
| SCHEMBL132928 | 1.00 | PNP (0.54) | PNPHSPA5HSPA8MEN1KMT2A | |
| Phosphoric Acid SCHEMBL7200240 | 0.96 | PNP (0.50) | PNPHSPA5HSPA8MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262254-B1 | 8-FLUORO-9-((2-HYDROXYETHOXY)METHYL))GUANINE / (8-FLUOROACYCLOVIR) USEFUL AS ANTICANCER AND ANTIVIRAL AGENT | THE REGENTS OF UNIV. OF CALIFORNIA | 2001-07-17 | — | — | US | disclosed |
| US-5861503-A | FLUORINATING WITH FLUORINE OR ACETYL HYPOFLUORITE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-01-19 | — | — | US | disclosed |