Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3971144 | 0.85 | TAS1R3 (0.51) | RAB9AHDAC6HDAC1HDAC8PLAU | |
| SCHEMBL8768105 | 0.85 | HSP90AA1 (0.49) | PLAUALDH1A1CYP2C9 | |
| SCHEMBL7797863 | 0.84 | P4HB (0.38) | P4HBRAB9ANPC1CRHBPCRHR2 | |
| Hydrochloric Acid SCHEMBL8506619 | 0.84 | HSP90AA1 (0.48) | PLAUALDH1A1CYP2C9 | |
| Hydrochloric Acid SCHEMBL8506547 | 0.84 | TAS1R3 (0.50) | HDAC6HDAC1HDAC8PLAUTAS1R3 | |
| Hydrochloric Acid SCHEMBL8506843 | 0.84 | MAPT (0.51) | RAB9ANPC1HDAC6HDAC1HDAC8 | |
| Hydrochloric Acid SCHEMBL7791921 | 0.83 | P4HB (0.38) | P4HBRAB9ANPC1CRHBPCRHR2 | |
| SCHEMBL7799908 | 0.81 | P4HB (0.40) | P4HBRAB9ANPC1CRHBPCRHR2 | |
| SCHEMBL21055125 | 0.81 | P4HB (0.46) | P4HBRAB9ANPC1HDAC6HDAC8 | |
| Hydrochloric Acid SCHEMBL7801204 | 0.80 | P4HB (0.40) | P4HBRAB9ANPC1CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262123-B1 | AS ANTIARRHYTHMIC AGENTS HAVING CARDIOPROTECTIVE COMPONENT, FOR PROPHYLAXIS AND TREATMENT OF INFARCTION AND ANGINA PECTORIS; FOR INHIBITION OF PATHOPHYSIOLOGICAL PROCESSES ASSOCIATED WITH GENESIS OF ISCHEMICALLY INDUCED DAMAGE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-07-17 | — | — | US | claimed |