Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TARBP2 | Q15633 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6873803 | 0.81 | HPGD (0.43) | POLBTSHRHPGDALDH1A1TARBP2 | |
| SCHEMBL23990453 | 0.80 | CYP1A2 (0.42) | NPC1TSHRHPGDALDH1A1TARBP2 | |
| SCHEMBL8957137 | 0.80 | KDM4E (0.46) | GAATSHRHPGDALDH1A1KDM4E | |
| SCHEMBL8920076 | 0.79 | CA12 (0.46) | NPC1HPGDALDH1A1TARBP2KDM4E | |
| SCHEMBL5750757 | 0.79 | ALDH1A1 (0.53) | NPC1POLBTSHRHPGDALDH1A1 | |
| SCHEMBL8957159 | 0.79 | TSHR (0.44) | GAATSHRHPGDALDH1A1TARBP2 | |
| SCHEMBL30281292 | 0.79 | HSP90AA1 (0.39) | TSHRHPGDALDH1A1TARBP2KDM4E | |
| SCHEMBL8957191 | 0.78 | MAPK1 (0.42) | GAATSHRALDH1A1KDM4EHSD17B10 | |
| SCHEMBL22727456 | 0.78 | TARBP2 (0.44) | POLBTSHRHPGDALDH1A1TARBP2 | |
| SCHEMBL26921830 | 0.78 | HTT (0.46) | GAANPC1HPGDALDH1A1TARBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265423-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE EUROPEEN DE BIOPROSPECTIVE-CEB (FR) | 2001-07-24 | — | — | US | disclosed |