SCHEMBL8957159

SCHEMBL8957159

CCOC(=O)c1conc1C(=O)Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.44
ALDH1A1 P00352 4/20 0.40
KDM4E B2RXH2 2/20 0.40
HPGD P15428 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
KMT2A Q03164 3/20 0.40
MEN1 O00255 2/20 0.40
HSD17B10 Q99714 1/20 0.39
GAA P10253 1/20 0.39
MAPK1 P28482 1/20 0.39
MAOB P27338 1/20 0.38
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA7 P43166 2/20 0.38
CA9 Q16790 2/20 0.38
CA14 Q9ULX7 2/20 0.38
CYP1A2 P05177 1/20 0.38
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8957137 0.85 KDM4E (0.46) TSHRALDH1A1KDM4EHPGDSMN1; SMN2
SCHEMBL8957191 0.80 MAPK1 (0.42) TSHRALDH1A1KDM4EKMT2AMEN1
SCHEMBL5410864 0.80 TSHR (0.50) TSHRALDH1A1KDM4EHPGDSMN1; SMN2
SCHEMBL7948540 0.79 GAA (0.42) TSHRALDH1A1KDM4EHPGDHSD17B10
SCHEMBL23991169 0.78 CA12 (0.49) TSHRALDH1A1KDM4EKMT2AMEN1
SCHEMBL162971 0.78 TSHR (0.48) TSHRALDH1A1KDM4EHPGDKMT2A
SCHEMBL5275787 0.77 TSHR (0.47) TSHRALDH1A1KDM4EKMT2AMEN1
SCHEMBL6873803 0.76 HPGD (0.43) TSHRALDH1A1KDM4EHPGDSMN1; SMN2
SCHEMBL7454997 0.76 ALDH1A1 (0.49) TSHRALDH1A1KDM4EHPGDHSD17B10
SCHEMBL23991100 0.75 TSHR (0.46) TSHRALDH1A1KDM4EHPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5576270-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1996-11-19 US disclosed