Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 2/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.37 |
| ▸ | OXTR | P30559 | 1/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984198 | 0.90 | TP53 (0.44) | TP53MEN1KMT2ANPC1TMEM97 | |
| Hydrochloric Acid SCHEMBL6984563 | 0.89 | F2 (0.40) | TP53NPC1THRBALDH1A1AVPR2 | |
| SCHEMBL7960198 | 0.88 | MEN1 (0.43) | TP53MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL7958428 | 0.88 | MEN1 (0.46) | TP53MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL6981025 | 0.87 | MEN1 (0.57) | TP53MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL6978699 | 0.84 | POLB (0.48) | TP53MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL6980414 | 0.84 | TP53 (0.44) | TP53MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL6980215 | 0.83 | TP53 (0.42) | TP53MEN1KMT2ANPC1TMEM97 | |
| SCHEMBL6984356 | 0.80 | SMN1; SMN2 (0.53) | TP53NPC1TMEM97SIGMAR1HDAC1 | |
| SCHEMBL7948557 | 0.80 | TP53 (0.45) | TP53MEN1KMT2ATHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |