Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983535 | 0.87 | TP53 (0.44) | TP53POLBMMP1KMT2AHDAC1 | |
| SCHEMBL6978698 | 0.86 | POLB (0.49) | TP53POLBMMP1KMT2AHDAC1 | |
| SCHEMBL6984356 | 0.84 | SMN1; SMN2 (0.53) | TP53HDAC1HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL6984198 | 0.81 | TP53 (0.44) | TP53KMT2AHDAC1HDAC8HDAC6 | |
| SCHEMBL6977738 | 0.80 | TP53 (0.51) | TP53POLBKMT2AHDAC1HDAC8 | |
| SCHEMBL7948560 | 0.80 | TP53 (0.43) | TP53KMT2AHDAC1HDAC8HDAC6 | |
| SCHEMBL6979412 | 0.80 | NAMPT (0.49) | TP53HDAC1HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL7085009 | 0.79 | TP53 (0.49) | TP53HDAC1HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL6981022 | 0.79 | TP53 (0.51) | TP53POLBHDAC1HDAC8HDAC6 | |
| SCHEMBL6985377 | 0.78 | RAB9A (0.62) | TP53POLBHDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |