Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | PTGIR | P43119 | 8/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958339 | 0.88 | PTGIR (0.36) | KDM4CPTGIRTBXA2RL3MBTL1DHFR | |
| SCHEMBL7948790 | 0.82 | SMN1; SMN2 (0.41) | PTGIRTBXA2RPTPN1MEN1KMT2A | |
| SCHEMBL8158814 | 0.80 | HPGD (0.40) | KDM4CL3MBTL1DHFRPDE4BPTPN1 | |
| SCHEMBL7952633 | 0.77 | KDM4C (0.33) | KDM4CPTGIRTBXA2R | |
| SCHEMBL5234354 | 0.73 | ALDH1A1 (0.46) | PTGIRTBXA2RHTR1AMEN1KMT2A | |
| SCHEMBL8601836 | 0.71 | SIGMAR1 (0.38) | KDM4CL3MBTL1DHFRPDE4B | |
| SCHEMBL21916301 | 0.71 | DHFR (0.38) | KDM4CL3MBTL1DHFRPDE4BPTPN1 | |
| SCHEMBL30788461 | 0.70 | KDM4C (0.41) | KDM4CL3MBTL1DHFRPDE4BPTPN1 | |
| SCHEMBL6342508 | 0.70 | KDM4C (0.41) | KDM4CL3MBTL1DHFRPDE4BPTPN1 | |
| SCHEMBL11057549 | 0.70 | KDM4C (0.44) | KDM4CL3MBTL1DHFRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323235-B1 | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS AND ENZYME INHIBITORS | OHTAKE ATSUSHI (JP) | 2001-11-27 | — | — | US | disclosed |
| US-6043264-A | A THROMBOXANE A2 RECEPTOR ANTAGONIST FOR TREATING HYPERTENSION, THROMBOSIS, ISCHEMIC HEART DISEASES, CIRCULATORY DISEASES, ARTERIOSCLEROSIS, PLATELET FUNCTION DISORDER, HYPERLIPIDEMIA, NEPHRITIS OR ASTHMA | TORAY INDUSTRIES, INC. (JP) | 2000-03-28 | — | — | US | disclosed |
| EP-0751126-A1 | BENZENE-FUSED HETEROCYCLIC DERIVATIVE AND USE OF THE SAME | TORAY INDUSTRIES, INC. (JP) | 1997-01-02 | — | — | EP | disclosed |