Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.49 |
| ▸ | ELANE | P08246 | 4/20 | 0.45 |
| ▸ | PLG | P00747 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7948778 | 0.84 | PPARG (0.60) | PPARGADORA3ACE2ELANEPLG | |
| SCHEMBL20630187 | 0.84 | ACE2 (0.54) | PPARGADORA3ACE2ELANEPLG | |
| SCHEMBL20630735 | 0.82 | ADORA3 (0.69) | PPARGADORA3ACE2ELANEPLG | |
| SCHEMBL31236659 | 0.82 | ADORA3 (0.69) | PPARGADORA3ACE2ELANEPLG | |
| Benzquercin SCHEMBL1057326 | 0.82 | PPARG (0.66) | PPARGADORA3ACE2ELANEPLG | |
| SCHEMBL28573367 | 0.80 | PPARG (0.53) | PPARGADORA3ACE2ELANEPLG | |
| SCHEMBL7940149 | 0.78 | PPARG (0.62) | PPARGADORA3ACE2ELANEPLG | |
| SCHEMBL16160543 | 0.78 | PPARG (0.58) | PPARGADORA3ACE2ELANEPLG | |
| SCHEMBL1421560 | 0.77 | ACE2 (0.69) | PPARGADORA3ACE2ELANEPLG | |
| SCHEMBL20631309 | 0.77 | ADORA3 (0.61) | PPARGADORA3ACE2ELANEPLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258840-B1 | ANTITUMOR AGENTS, ANTIINFLAMMATORY AGENTS, ENZYME INHIBITORS OF KINASES | COBRA THERAPEUTICS LIMITED (GB) | 2001-07-10 | — | — | US | disclosed |
| EP-0912541-A1 | ANALOGUES OR DERIVATIVES OF QUERCETIN (PRODRUGS) | Cobra Therapeutics Limited (GB) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997049693-A1 | ANALOGUES OR DERIVATIVES OF QUERCETIN (PRODRUGS) | COBRA THERAPEUTICS LIMITED (GB) | 1997-12-31 | — | — | WO | disclosed |