Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | KDM4A | O75164 | 1/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29973281 | 1.00 | MEN1 (0.51) | MEN1KMT2AGAAUSP2KDM4E | |
| SCHEMBL28160161 | 0.89 | ALDH1A1 (0.52) | MEN1KMT2AGAAUSP2KDM4E | |
| SCHEMBL7619422 | 0.88 | LMNA (0.48) | MEN1KMT2AGAAUSP2KDM4E | |
| SCHEMBL15137975 | 0.87 | MEN1 (0.42) | MEN1KMT2AGAAUSP2KDM4E | |
| SCHEMBL29542545 | 0.84 | ALDH1A1 (0.53) | MEN1KMT2AGAAUSP2KDM4E | |
| SCHEMBL3905172 | 0.84 | ALDH1A1 (0.53) | MEN1KMT2AGAAUSP2KDM4E | |
| SCHEMBL10621054 | 0.83 | LMNA (0.50) | MEN1KMT2AGAAUSP2KDM4E | |
| SCHEMBL21142245 | 0.81 | SMN1; SMN2 (0.46) | MEN1KMT2AGAAUSP2KDM4E | |
| SCHEMBL12307044 | 0.81 | SMN1; SMN2 (0.54) | MEN1KMT2AGAAUSP2KDM4E | |
| SCHEMBL21929776 | 0.81 | SRD5A1 (0.44) | MEN1KMT2AUSP2KDM4EKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297270-B1 | HERBICIDE; DYES INTERMEDIATE, AMINO ACIDS, PHOTOSENSITIVE AND/OR THERMOSENSITIVE MATERIAL; COSMETICS; ANTIOXIDANT; ANGIOTENSIN(II) ANTAGONIST; CALCIUM CHANNEL BLOCKER, ENZYME INHIBITOR; POLYMERIZATION CATALYST | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 2001-10-02 | — | — | US | claimed |
| EP-1004579-A1 | Process for the preparation of 2,3-Dihydroindoles (Indolines), certain 2,3-Dihydroindoles and their use | Aventis Research & Technologies GmbH & Co KG (DE) | 2000-05-31 | — | — | EP | claimed |
| US-6297270-B1 | HERBICIDE; DYES INTERMEDIATE, AMINO ACIDS, PHOTOSENSITIVE AND/OR THERMOSENSITIVE MATERIAL; COSMETICS; ANTIOXIDANT; ANGIOTENSIN(II) ANTAGONIST; CALCIUM CHANNEL BLOCKER, ENZYME INHIBITOR; POLYMERIZATION CATALYST | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 2001-10-02 | — | — | US | disclosed |
| EP-1004579-A1 | Process for the preparation of 2,3-Dihydroindoles (Indolines), certain 2,3-Dihydroindoles and their use | Aventis Research & Technologies GmbH & Co KG (DE) | 2000-05-31 | — | — | EP | disclosed |
| EP-1004579-A1 | Process for the preparation of 2,3-Dihydroindoles (Indolines), certain 2,3-Dihydroindoles and their use | Aventis Research & Technologies GmbH & Co KG (DE) | 2000-05-31 | — | — | EP | disclosed |