Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 9/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6985093 | 0.90 | NR3C1 (0.53) | NR3C1SMN1; SMN2KMT2AMEN1TP53 | |
| Hydrochloric Acid SCHEMBL6982871 | 0.89 | NR3C1 (0.52) | NR3C1SMN1; SMN2KMT2AMEN1BRD4 | |
| SCHEMBL6982740 | 0.89 | NR3C1 (0.59) | NR3C1SMN1; SMN2KMT2AMEN1TP53 | |
| Hydrochloric Acid SCHEMBL6981078 | 0.88 | NR3C1 (0.58) | NR3C1SMN1; SMN2KMT2AMEN1TP53 | |
| Hydrochloric Acid SCHEMBL6980868 | 0.86 | NR3C1 (0.56) | NR3C1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6979366 | 0.85 | NR3C1 (0.54) | NR3C1SMN1; SMN2KMT2AMEN1BRD4 | |
| Hydrochloric Acid SCHEMBL6980119 | 0.85 | NR3C1 (0.56) | NR3C1SMN1; SMN2KMT2ATP53MAPT | |
| Hydrochloric Acid SCHEMBL7409665 | 0.85 | NR3C1 (0.54) | NR3C1SMN1; SMN2KMT2AMEN1BRD4 | |
| SCHEMBL6982229 | 0.83 | NR3C1 (0.60) | NR3C1SMN1; SMN2KMT2AMEN1TP53 | |
| Hydrochloric Acid SCHEMBL7403126 | 0.83 | KMT2A (0.53) | NR3C1SMN1; SMN2KMT2AMEN1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |