Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 11/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6981078 | 0.99 | NR3C1 (0.58) | NR3C1SMN1; SMN2MEN1KMT2ATP53 | |
| Hydrochloric Acid SCHEMBL6980868 | 0.97 | NR3C1 (0.56) | NR3C1SMN1; SMN2MEN1KMT2AF2 | |
| Hydrochloric Acid SCHEMBL6976392 | 0.94 | KMT2A (0.53) | NR3C1SMN1; SMN2MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL6985288 | 0.92 | OGG1 (0.49) | NR3C1TP53F2 | |
| SCHEMBL6977840 | 0.92 | NR3C1 (0.53) | NR3C1SMN1; SMN2MEN1KMT2ATP53 | |
| Hydrochloric Acid SCHEMBL6976598 | 0.91 | NR3C1 (0.49) | NR3C1SMN1; SMN2MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL6980119 | 0.91 | NR3C1 (0.56) | NR3C1SMN1; SMN2KMT2ATP53MAPT | |
| Hydrochloric Acid SCHEMBL6986046 | 0.91 | NR3C1 (0.52) | NR3C1SMN1; SMN2MEN1KMT2ATP53 | |
| Hydrochloric Acid SCHEMBL6985450 | 0.91 | ADRB2 (0.56) | NR3C1SMN1; SMN2MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL6977280 | 0.90 | NR3C1 (0.61) | NR3C1SMN1; SMN2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | claimed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | claimed |
| EP-0991624-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | Boehringer Ingelheim Pharma KG (DE) | 2000-04-12 | — | — | EP | claimed |
| WO-1999000371-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-01-07 | — | — | WO | claimed |
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |
| EP-0991624-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | Boehringer Ingelheim Pharma KG (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999000371-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-01-07 | — | — | WO | disclosed |