Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | SQLE | Q14534 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | POLA1 | P09884 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7948993 | 1.00 | LMNA (0.54) | LMNAALDH1A1SQLETSHREPHX2 | |
| SCHEMBL16021161 | 0.87 | LMNA (0.54) | LMNAALDH1A1TSHREPHX2CNR2 | |
| SCHEMBL11577022 | 0.85 | ALDH1A1 (0.56) | LMNAALDH1A1TSHREPHX2CNR2 | |
| SCHEMBL11577020 | 0.85 | ALDH1A1 (0.56) | LMNAALDH1A1TSHREPHX2CNR2 | |
| SCHEMBL7949308 | 0.83 | LMNA (0.50) | LMNAALDH1A1TSHREPHX2CNR2 | |
| SCHEMBL7951003 | 0.83 | LMNA (0.50) | LMNAALDH1A1TSHREPHX2CNR2 | |
| SCHEMBL7949305 | 0.83 | LMNA (0.50) | LMNAALDH1A1TSHREPHX2CNR2 | |
| SCHEMBL25400130 | 0.82 | ALDH1A1 (0.61) | LMNAALDH1A1TSHREPHX2CNR2 | |
| SCHEMBL7941250 | 0.82 | ALDH1A1 (0.61) | LMNAALDH1A1TSHREPHX2CNR2 | |
| SCHEMBL3706941 | 0.82 | ALDH1A1 (0.61) | LMNAALDH1A1TSHREPHX2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255276-B1 | MUSK MACROMOLECULE | GIVAUDEN ROURE (INTERNATIONAL) S.A. (CH) | 2001-07-03 | — | — | US | disclosed |
| EP-0908455-A1 | Macrocycles | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1999-04-14 | — | — | EP | disclosed |