Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 15/20 | 0.66 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961381 | 0.91 | DRD2 (0.64) | DRD2DRD4DRD3CCR1ADRA1A | |
| SCHEMBL7949530 | 0.83 | DRD2 (0.56) | DRD2DRD4DRD3CCR1ADRA1A | |
| SCHEMBL7959857 | 0.82 | DRD2 (0.46) | DRD2DRD4DRD3CCR1KMT2A | |
| SCHEMBL7957165 | 0.80 | DRD2 (0.66) | DRD2CCR1ADRA1A | |
| SCHEMBL3856163 | 0.79 | DRD2 (0.61) | DRD2DRD4DRD3CCR1 | |
| SCHEMBL3856503 | 0.79 | DRD2 (0.65) | DRD2DRD4DRD3CCR1 | |
| SCHEMBL7960076 | 0.79 | DRD2 (0.70) | DRD2DRD4DRD3ADRA1AKMT2A | |
| SCHEMBL7964044 | 0.79 | DRD2 (0.53) | DRD2DRD4DRD3ADRA1A | |
| SCHEMBL7949576 | 0.78 | DRD2 (0.48) | DRD2DRD4DRD3KMT2ACACNA1G | |
| SCHEMBL7961473 | 0.78 | DRD2 (0.58) | DRD2DRD4DRD3ADRA1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187774-B1 | N-PIPERAZINYLALKYLINDAZOLE DERIVATIVES; PSYCHOLOGICAL DISORDERS, SCHIZOPHRENIA; SIDE EFFECT REDUCTION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0885883-A1 | FUSED HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |