Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.56 |
| ▸ | CCR1 | P32246 | 6/20 | 0.47 |
| ▸ | DRD3 | P35462 | 4/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961380 | 0.92 | DRD2 (0.54) | DRD2CCR1DRD3DRD4ADRA1D | |
| SCHEMBL7959852 | 0.83 | KDM4E (0.47) | DRD2CCR1DRD3FAAHADRA1A | |
| SCHEMBL7949532 | 0.83 | DRD2 (0.66) | DRD2CCR1DRD3DRD4ADRA1A | |
| SCHEMBL7957164 | 0.81 | DRD2 (0.56) | DRD2CCR1 | |
| SCHEMBL7960074 | 0.81 | DRD2 (0.62) | DRD2CCR1ADRA1A | |
| SCHEMBL7949574 | 0.80 | DRD2 (0.46) | DRD2DRD3DRD4 | |
| SCHEMBL7961470 | 0.80 | DRD2 (0.49) | DRD2CCR1 | |
| SCHEMBL7964042 | 0.80 | DRD2 (0.46) | DRD2CCR1DRD3DRD4 | |
| SCHEMBL7959911 | 0.79 | CCR1 (0.45) | DRD2CCR1DRD3DRD4 | |
| SCHEMBL7949042 | 0.78 | CCR1 (0.52) | DRD2CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187774-B1 | N-PIPERAZINYLALKYLINDAZOLE DERIVATIVES; PSYCHOLOGICAL DISORDERS, SCHIZOPHRENIA; SIDE EFFECT REDUCTION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0885883-A1 | FUSED HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |