Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958066 | 0.82 | CYP1A2 (0.57) | LMNAHTTTP53SMN1; SMN2TSHR | |
| SCHEMBL7949780 | 0.81 | LMNA (0.64) | LMNAHTTTP53SMN1; SMN2TSHR | |
| SCHEMBL7960553 | 0.81 | LMNA (0.57) | LMNAHTTTP53SMN1; SMN2TSHR | |
| SCHEMBL11376226 | 0.80 | LMNA (0.63) | LMNAHTTTP53SMN1; SMN2TSHR | |
| SCHEMBL8314561 | 0.79 | LMNA (0.55) | LMNAHTTTP53SMN1; SMN2TSHR | |
| SCHEMBL7960609 | 0.79 | ESR1 (0.55) | LMNASMN1; SMN2L3MBTL1CA12CA9 | |
| SCHEMBL24864752 | 0.77 | FLT3 (0.59) | LMNAHTTSMN1; SMN2TSHRMAPK1 | |
| SCHEMBL7907536 | 0.77 | LMNA (0.56) | LMNAHTTTP53SMN1; SMN2TSHR | |
| SCHEMBL7965505 | 0.75 | LMNA (0.57) | LMNAHTTTP53SMN1; SMN2TSHR | |
| SCHEMBL17169392 | 0.75 | LMNA (0.86) | LMNAHTTTP53SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184245-B1 | Cyclic ketone derivatives and their medical applications | TORAY INDUSTRIES INC. (JP) | 2001-02-06 | — | — | US | disclosed |