Dibromomethane

Dibromomethane

SCHEMBL7950072

BrCBr.c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.75
CYP3A4 P08684 1/20 0.75
ESR1 P03372 4/20 0.55
ESR2 Q92731 4/20 0.55
ALDH1A1 P00352 3/20 0.43
TRPA1 O75762 1/20 0.43
TSHR P16473 1/20 0.43
KDM4E B2RXH2 1/20 0.42
GAA P10253 1/20 0.42
PTPN1 P18031 1/20 0.35
GSK3B P49841 1/20 0.35
NPSR1 Q6W5P4 1/20 0.33
CALM1 P0DP23 1/20 0.33
DRD1 P21728 2/20 0.32
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
LMNA P02545 1/20 0.32
HPGD P15428 1/20 0.32
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dibromomethane SCHEMBL5329477 1.00 TDP1 (0.75) TDP1CYP3A4ESR1ESR2ALDH1A1
1,2-Dibromoethane SCHEMBL28837174 0.91 TDP1 (0.71) TDP1CYP3A4ESR1ESR2ALDH1A1
SCHEMBL5356053 0.88 TDP1 (0.67) TDP1CYP3A4ESR1ESR2ALDH1A1
Bromoethane SCHEMBL43961 0.88 TDP1 (0.67) TDP1CYP3A4ESR1ESR2ALDH1A1
Hydrochloric Acid SCHEMBL11863762 0.87 TDP1 (0.86) TDP1CYP3A4ESR1ESR2ALDH1A1
SCHEMBL5028587 0.87 TDP1 (1.00) TDP1CYP3A4ESR1ESR2ALDH1A1
SCHEMBL101 0.87 TDP1 (1.00) TDP1CYP3A4ESR1ESR2ALDH1A1
Benzene SCHEMBL6890099 0.87 TDP1 (1.00) TDP1CYP3A4ESR1ESR2ALDH1A1
SCHEMBL2085135 0.87 TDP1 (1.00) TDP1CYP3A4ESR1ESR2ALDH1A1
SCHEMBL319391 0.86 TDP1 (0.63) TDP1CYP3A4ESR1ESR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001038287-A1 ADDUCTS OF GLYCIDYLESTERS OF α,α-BRANCHED CARBOXYLIC ACIDS AND CARBOXYLIC ACIDS AND PROCESS FOR THEIR PREPARATION RESOLUTION RESEARCH NEDERLAND B.V. (NL) 2001-05-31 WO disclosed
EP-0244015-B1 DEACTIVATION OF PHOSPHONIUM SALT CATALYST SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-07-15 EP disclosed
EP-0209174-B1 PROCESS FOR PREPARING ADVANCED EPOXY RESIN COMPOSITIONS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-03-04 EP disclosed
EP-0244015-A2 Deactivation of phosphonium salt catalyst SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1987-11-04 EP disclosed
EP-0209174-A2 Process for preparing advanced epoxy resin compositions SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1987-01-21 EP disclosed