Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.75 |
| ▸ | ESR1 | P03372 | 4/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 2/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dibromomethane SCHEMBL7950072 | 1.00 | TDP1 (0.75) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| 1,2-Dibromoethane SCHEMBL28837174 | 0.91 | TDP1 (0.71) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL5356053 | 0.88 | TDP1 (0.67) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| Bromoethane SCHEMBL43961 | 0.88 | TDP1 (0.67) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11863762 | 0.87 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL5028587 | 0.87 | TDP1 (1.00) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL101 | 0.87 | TDP1 (1.00) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| Benzene SCHEMBL6890099 | 0.87 | TDP1 (1.00) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL2085135 | 0.87 | TDP1 (1.00) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL319391 | 0.86 | TDP1 (0.63) | TDP1CYP3A4ESR1ESR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240351970-A1 | PREPARATION METHOD OF 5-BROMO-2-CHLORO-BENZOIC ACID AS A SYNTHETIC RAW MATERIAL FOR HYPOGLYCEMIC DRUGS | ZHEJIANG AUSUN PHARMACEUTICAL CO., LTD. (CN) | 2024-10-24 | — | — | US | claimed |
| EP-4389733-A1 | METHOD FOR PREPARING 5-BROMO-2-CHLORO-BENZOIC ACID AS RAW MATERIAL IN HYPOGLYCEMIC DRUG SYNTHESIS | Zhejiang Ausun Pharmaceutical Co., Ltd. (CN) | 2024-06-26 | — | — | EP | claimed |
| CN-113773194-B | Preparation method of 5-bromo-2-chloro-benzoic acid as synthesis raw material of hypoglycemic agent | 浙江奥翔药业股份有限公司 | 2023-05-02 | — | — | CN | claimed |
| CN-113773194-A | Preparation method of 5-bromo-2-chloro-benzoic acid as hypoglycemic drug synthesis raw material | 浙江奥翔药业股份有限公司 | 2021-12-10 | — | — | CN | claimed |
| WO-2025200154-A1 | TWO-PART EPOXY COMPOSITION COMPRISING THIOL CURATIVE, AND CATALYST | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2025-10-02 | — | — | WO | disclosed |
| CN-120202211-A | Cyclic compounds having selective KRAS inhibition over HRAS and NRAS | 中外制药株式会社 | 2025-06-24 | — | — | CN | disclosed |
| CN-118843613-A | RXFP1 agonists | 百时美施贵宝公司 | 2024-10-25 | — | — | CN | disclosed |
| US-20240351970-A1 | PREPARATION METHOD OF 5-BROMO-2-CHLORO-BENZOIC ACID AS A SYNTHETIC RAW MATERIAL FOR HYPOGLYCEMIC DRUGS | ZHEJIANG AUSUN PHARMACEUTICAL CO., LTD. (CN) | 2024-10-24 | — | — | US | disclosed |
| CN-114555592-B | 2-Azaspiro [3.4] octane derivatives as M4 agonists | 诺华股份有限公司 | 2024-09-06 | — | — | CN | disclosed |
| EP-4389733-A1 | METHOD FOR PREPARING 5-BROMO-2-CHLORO-BENZOIC ACID AS RAW MATERIAL IN HYPOGLYCEMIC DRUG SYNTHESIS | Zhejiang Ausun Pharmaceutical Co., Ltd. (CN) | 2024-06-26 | — | — | EP | disclosed |
| CN-118119613-A | Benzimidazoles as IL-17 modulators | 詹森药业有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-112236431-B | Purinone Compounds and Their Use in the Treatment of Cancer | 阿斯利康(瑞典)有限公司 | 2024-02-13 | — | — | CN | disclosed |
| WO-2000044737-A1 | AMINOALKYLBENZOFURANS AS SEROTONIN (5-HT(2C)) AGONISTS | ELI LILLY AND COMPANY (US) | 2000-08-03 | — | — | WO | disclosed |
| WO-1998020878-A1 | 5-[φ-(SUBSTITUTED ARYL)ALKENYLENE AND ALKYNYLENE]-2,4-DIAMINOPYRIMIDINES AS PESTICIDES | FMC CORPORATION (US) | 1998-05-22 | — | — | WO | disclosed |
| US-5696259-A | 2,4-diamino-5-iodopyrimidines useful as pesticide intermediates | FMC CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |
| US-5622954-A | INSECTICIDE | FMC CORPORATION (US) | 1997-04-22 | — | — | US | disclosed |
| WO-1996037511-A1 | CYCLIC PEPTIDES ANTIFUNGAL AGENTS | ELI LILLY AND COMPANY (US) | 1996-11-28 | — | — | WO | disclosed |
| US-5502054-A | LARVACIDES FOR INSECTS SUCH AS TOBACCO BUDWORM | FMC CORPORATION (US) | 1996-03-26 | — | — | US | disclosed |
| US-5187175-A | 2-carbonyl substituted-5-hydroxy-1, 3-pyrimidines as antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1993-02-16 | — | — | US | disclosed |
| EP-0082498-A2 | Beta-lactam compounds and process for the preparation thereof | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1983-06-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240351970-A1 | PREPARATION METHOD OF 5-BROMO-2-CHLORO-BENZOIC ACID AS A SYNTHETIC RAW MATERIAL FOR HYPOGLYCEMIC DRUGS | GABRA5, DDC, GCG | TDP1 4050/4885CYP3A4 135/4885ESR1 3042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.