Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958068 | 1.00 | MAPT (0.40) | MAPTALDH1A1L3MBTL1NPC1MEN1 | |
| SCHEMBL7949759 | 1.00 | MAPT (0.40) | MAPTALDH1A1L3MBTL1NPC1MEN1 | |
| SCHEMBL7964591 | 0.99 | MAPT (0.38) | MAPTALDH1A1L3MBTL1NPC1MEN1 | |
| SCHEMBL7960775 | 0.90 | LPAR1 (0.39) | ALDH1A1FAAHTRPV1HPGD | |
| SCHEMBL7960122 | 0.90 | LPAR1 (0.39) | ALDH1A1FAAHTRPV1HPGD | |
| SCHEMBL7949624 | 0.90 | LPAR1 (0.39) | ALDH1A1FAAHTRPV1HPGD | |
| SCHEMBL9595748 | 0.90 | MAPT (0.42) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL7958051 | 0.88 | ALDH1A1 (0.39) | ALDH1A1FAAHTRPV1HPGD | |
| SCHEMBL9595918 | 0.88 | MAPT (0.40) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL7958124 | 0.86 | SMN1; SMN2 (0.35) | MAPTALDH1A1MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172255-B1 | INSECTICIDES; MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-09 | — | — | US | disclosed |
| US-5830826-A | Alkoxy-alkyl-substituted 1H-3-aryl-pyrrolidine-2, 4-diones used as herbicicides and pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |