SCHEMBL7958124

SCHEMBL7958124

COC(=O)C1(NC(=O)Cc2c(C)cc(OC)cc2C)CCC(C)CC1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.35
KMT2A Q03164 2/20 0.35
ALDH1A1 P00352 2/20 0.34
GAA P10253 2/20 0.34
HPGD P15428 2/20 0.34
MAPT P10636 2/20 0.34
APOBEC3A P31941 1/20 0.34
APOBEC3G Q9HC16 1/20 0.34
TSHR P16473 1/20 0.34
LPAR1 Q92633 1/20 0.33
CYP3A4 P08684 1/20 0.33
MEN1 O00255 1/20 0.32
P2RX7 Q99572 1/20 0.32
EPHX2 P34913 1/20 0.32
GPR132 Q9UNW8 1/20 0.32
MTNR1A P48039 1/20 0.31
MTNR1B P49286 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7950121 0.91 GPR132 (0.39) SMN1; SMN2KMT2AALDH1A1GAAHPGD
SCHEMBL8905682 0.90 MAPT (0.34) GAAHPGDMAPTLPAR1P2RX7
SCHEMBL7961454 0.88 KMT2A (0.35) KMT2AALDH1A1HPGDMAPTAPOBEC3A
SCHEMBL7964591 0.88 MAPT (0.38) KMT2AALDH1A1HPGDMAPTTSHR
SCHEMBL7957823 0.87 ALDH1A1 (0.35) KMT2AALDH1A1HPGDMAPTCYP3A4
SCHEMBL7958195 0.87 LMNA (0.33) KMT2AALDH1A1HPGDMAPTAPOBEC3A
SCHEMBL7960343 0.87 HPGD (0.34) KMT2AALDH1A1HPGDAPOBEC3AAPOBEC3G
SCHEMBL7949759 0.86 MAPT (0.40) KMT2AALDH1A1HPGDMAPTCYP3A4
SCHEMBL7958068 0.86 MAPT (0.40) KMT2AALDH1A1HPGDMAPTCYP3A4
SCHEMBL7950104 0.86 MAPT (0.40) KMT2AALDH1A1HPGDMAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6172255-B1 INSECTICIDES; MITICIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-01-09 US disclosed
US-5830826-A Alkoxy-alkyl-substituted 1H-3-aryl-pyrrolidine-2, 4-diones used as herbicicides and pesticides BAYER AKTIENGESELLSCHAFT (DE) 1998-11-03 US disclosed