Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3239988 | 0.85 | PPARG (0.36) | ARS1PR1PPARGPPARDPPARA | |
| SCHEMBL8266091 | 0.85 | CSNK2A1 (0.40) | ARS1PR1PPARGPPARDPPARA | |
| SCHEMBL25369859 | 0.84 | KIF11 (0.49) | ARKIF11S1PR1CYP4F2CYP4A11 | |
| SCHEMBL30694777 | 0.84 | KIF11 (0.49) | ARKIF11S1PR1CYP4F2CYP4A11 | |
| SCHEMBL5371918 | 0.81 | AR (0.54) | ARKIF11S1PR1PPARGPPARD | |
| SCHEMBL88794 | 0.80 | L3MBTL1 (0.45) | ARPPARGPPARAHTTKDM4E | |
| SCHEMBL3071677 | 0.80 | CYP4F2 (0.54) | CYP4F2CYP4A11RENKDM4EKMT2A | |
| SCHEMBL89647 | 0.79 | S1PR4 (0.41) | ARHTTKDM4EKMT2APOLB | |
| SCHEMBL8237989 | 0.79 | HTT (0.39) | ARS1PR1HTTKDM4EKMT2A | |
| SCHEMBL7952850 | 0.78 | CYP3A4 (0.44) | ARLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024772-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-03-04 | — | — | WO | disclosed |